Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression

The physical properties of the extracellular matrix (ECM), such as stiffness, are involved in the determination of the characteristics of cancer cells, including chemotherapy sensitivity. Resistance to chemotherapy is often linked to dysfunction of tumor suppressor p53; however, it remains elusive w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomed Res Int
Egile Nagusiak: Ebata, Takahiro, Mitsui, Yasumasa, Sugimoto, Wataru, Maeda, Miho, Araki, Keigo, Machiyama, Hiroaki, Harada, Ichiro, Sawada, Yasuhiro, Fujita, Hideaki, Hirata, Hiroaki, Kawauchi, Keiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278210/
https://ncbi.nlm.nih.gov/pubmed/28191463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5158961
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