Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression

The physical properties of the extracellular matrix (ECM), such as stiffness, are involved in the determination of the characteristics of cancer cells, including chemotherapy sensitivity. Resistance to chemotherapy is often linked to dysfunction of tumor suppressor p53; however, it remains elusive w...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Ebata, Takahiro, Mitsui, Yasumasa, Sugimoto, Wataru, Maeda, Miho, Araki, Keigo, Machiyama, Hiroaki, Harada, Ichiro, Sawada, Yasuhiro, Fujita, Hideaki, Hirata, Hiroaki, Kawauchi, Keiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278210/
https://ncbi.nlm.nih.gov/pubmed/28191463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5158961
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi