Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of senescent and quiescent human fibroblasts.

Insulin-like growth factor binding protein 3 (IGFBP-3) mRNA levels were consistently higher in both senescent normal human diploid fibroblasts (HDFs) at late passage (old cells) and prematurely senescent HDFs from a subject with Werner syndrome (WS) during serum depletion and repletion of growth med...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Goldstein, S, Moerman, E J, Jones, R A, Baxter, R C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9680
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