Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway

Background. Histone deacetylases (HDACs) play a pivotal role in signaling modification and gene transcriptional regulation that are essential for cardiovascular pathophysiology. Diabetic hearts with higher HDACs activity were more vulnerable to myocardial ischemia/reperfusion (MI/R) injury compared...

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Dades bibliogràfiques
Publicat a:J Diabetes Res
Autors principals: Wu, Yang, Leng, Yan, Meng, Qingtao, Xue, Rui, Zhao, Bo, Zhan, Liying, Xia, Zhongyuan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278197/
https://ncbi.nlm.nih.gov/pubmed/28191472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8208065
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