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Solid-State (13)C NMR Reveals Annealing of Raft-Like Membranes Containing Cholesterol by the Intrinsically Disordered Protein α-Synuclein
Misfolding and aggregation of the intrinsically disordered protein α-Synuclein (αS) in Lewy body plaques is a characteristic marker of late-stage Parkinson’s disease. It is well established that membrane binding is initiated at the N-terminus of the protein and affects biasing of conformational ense...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5276865/ https://ncbi.nlm.nih.gov/pubmed/23583776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.002 |
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