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Cyclic AMP Recruits a Discrete Intracellular Ca(2+) Store by Unmasking Hypersensitive IP(3) Receptors
Inositol 1,4,5-trisphosphate (IP(3)) stimulates Ca(2+) release from the endoplasmic reticulum (ER), and the response is potentiated by 3′,5′-cyclic AMP (cAMP). We investigated this interaction in HEK293 cells using carbachol and parathyroid hormone (PTH) to stimulate formation of IP(3) and cAMP, res...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5276804/ https://ncbi.nlm.nih.gov/pubmed/28099849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.058 |
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