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Antagonizing Retinoic Acid Receptors Increases Myeloid Cell Production by Cultured Human Hematopoietic Stem Cells

Activities of the retinoic acid receptor (RAR)α and RARγ are important to hematopoiesis. Here, we have investigated the effects of receptor selective agonists and antagonists on the primitive human hematopoietic cell lines KG1 and NB-4 and purified normal human hematopoietic stem cells (HSCs). Agoni...

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Detalhes bibliográficos
Publicado no:Arch Immunol Ther Exp (Warsz)
Main Authors: Brown, Geoffrey, Marchwicka, Aleksandra, Cunningham, Alan, Toellner, Kai-Michael, Marcinkowska, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274652/
https://ncbi.nlm.nih.gov/pubmed/27412076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00005-016-0411-0
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