NADPH-Cytochrome P450 Reductase Is Regulated by All-Trans Retinoic Acid and by 1,25-Dihydroxyvitamin D(3) in Human Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) cell lines can be driven to differentiate to monocyte-like cells by 1,25- dihydroxyvitamin D(3) (1,25D) and to granulocyte-like cells by all-trans-retinoic acid (ATRA). Both compounds activate their specific intracellular receptors, vitamin D receptor (VDR) and retinoic...

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Autores principales: Gocek, Elżbieta, Marchwicka, Aleksandra, Bujko, Kamila, Marcinkowska, Ewa
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958372/
https://ncbi.nlm.nih.gov/pubmed/24642534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091752
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