Ex-vivo iTreg differentiation revisited: Convenient alternatives to existing strategies

Ex-vivo differentiation of regulatory T cells (Tregs) from naïve CD4(+) T-cells has been widely used in immunological research. Isolation of a highly pure naïve T cell population is the key factor that determines the efficiency of subsequent Treg differentiation. Currently, this step relies mostly o...

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Pubblicato in:J Immunol Methods
Autori principali: Akkaya, Billur, Holstein, Amanda H., Isaac, Christopher, Maz, Mitra P., Glass, Deborah D., Shevach, Ethan M., Akkaya, Munir
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274576/
https://ncbi.nlm.nih.gov/pubmed/27919837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2016.11.013
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