Deletion of Macrophage Migration Inhibitory Factor Reduces Severity of Osteoarthritis in Aged Mice

OBJECTIVE: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that is elevated in the serum and synovial fluid of osteoarthritic (OA) patients. In this study, the potential role of MIF in OA was studied using human joint tissues and in vivo in mice with age-related and surgi...

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Publicado no:Arthritis Rheumatol
Main Authors: Rowe, Meredith A., Harper, Lindsey R., McNulty, Margaret A., Lau, Anthony G., Carlson, Cathy S., Leng, Lin, Bucala, Richard J., Miller, Richard A., Loeser, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274570/
https://ncbi.nlm.nih.gov/pubmed/27564840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39844
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