Tracking Monocyte Recruitment and Macrophage Accumulation in Atherosclerotic Plaque Progression Using a Novel hCD68GFP/ApoE(−/−) Reporter Mouse—Brief Report

OBJECTIVE—: To create a model of atherosclerosis using green fluorescent protein (GFP)–targeted monocytes/macrophages, allowing analysis of both endogenous GFP(+) and adoptively transferred GFP(+) myeloid cells in arterial inflammation. APPROACH AND RESULTS—: hCD68GFP reporter mice were crossed with...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: McNeill, Eileen, Iqbal, Asif J., Jones, Daniel, Patel, Jyoti, Coutinho, Patricia, Taylor, Lewis, Greaves, David R., Channon, Keith M.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Basic Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274540/
https://ncbi.nlm.nih.gov/pubmed/27908893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308367
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