Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe(–/–) mice during disease regression

Experimental models of atherosclerosis suggest that recruitment of monocytes into plaques drives the progression of this chronic inflammatory condition. Cholesterol-lowering therapy leads to plaque stabilization or regression in human atherosclerosis, characterized by reduced macrophage content, but...

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Autors principals: Potteaux, Stephane, Gautier, Emmanuel L., Hutchison, Susan B., van Rooijen, Nico, Rader, Daniel J., Thomas, Michael J., Sorci-Thomas, Mary G., Randolph, Gwendalyn J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083793/
https://ncbi.nlm.nih.gov/pubmed/21505265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43802
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