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Establishment of a rat model with diet-induced coronary atherosclerosis

Coronary atherosclerotic disease is a serious disease in humans, but no suitable animal model is available currently for further studies. We used apolipoprotein E gene knockout (ApoE KO) rats to induce hypercholesterolemia through a special high cholesterol/bile salt diet (Paigen diet), then analyze...

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Detalhes bibliográficos
Publicado no:J Biomed Res
Main Authors: Gao, Mingming, Xin, Guo, Qiu, Xu, Wang, Yuhui, Liu, George
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274512/
https://ncbi.nlm.nih.gov/pubmed/28808185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.31.20160020
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