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Cellular permeation of large molecules mediated by TRPM8 channels

While most membrane channels are only capable of passing small ions, certain non-selective cation channels have been recently shown to have the capacity to permeate large cations. The mechanisms underlying large molecule permeation are unclear, but this property has been exploited pharmacologically...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: McCoy, Daniel D., Palkar, Radhika, Yang, Yuening, Ongun, Serra, McKemy, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272863/
https://ncbi.nlm.nih.gov/pubmed/28038937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.12.063
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