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Pharmacological Blockade of TRPM8 Ion Channels Alters Cold and Cold Pain Responses in Mice
TRPM8 (Transient Receptor Potential Melastatin-8) is a cold- and menthol-gated ion channel necessary for the detection of cold temperatures in the mammalian peripheral nervous system. Functioning TRPM8 channels are required for behavioral responses to innocuous cool, noxious cold, injury-evoked cold...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184174/ https://ncbi.nlm.nih.gov/pubmed/21984952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025894 |
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