Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation

Orphan GPCRs provide an opportunity to identify potential pharmacological targets, yet their expression patterns and physiological functions remain challenging to elucidate. Here, we have used a genetically engineered knockin reporter mouse to map the expression pattern of the Gpr182 during developm...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kechele, Daniel O., Blue, R. Eric, Zwarycz, Bailey, Espenschied, Scott T., Mah, Amanda T., Siegel, Marni B., Perou, Charles M., Ding, Shengli, Magness, Scott T., Lund, P. Kay, Caron, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272174/
https://ncbi.nlm.nih.gov/pubmed/28094771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87588
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