The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts

We previously identified several mRNAs encoding components of the secretory pathway, including signal recognition particle (SRP) subunit mRNAs, among transcripts associated with the RNA-binding protein CELF1. Through immunoprecipitation of RNAs crosslinked to CELF1 in myoblasts and in vitro binding...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Russo, Joseph, Lee, Jerome E., López, Carolina M., Anderson, John, Nguyen, Thuy-mi P., Heck, Adam M., Wilusz, Jeffrey, Wilusz, Carol J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271678/
https://ncbi.nlm.nih.gov/pubmed/28129347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170680
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