Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms

FOXC1 loss contributes to Dandy-Walker malformation (DWM), a common human cerebellar malformation. Previously, we found that complete Foxc1 loss leads to aberrations in proliferation, neuronal differentiation and migration in the embryonic mouse cerebellum (Haldipur et al., 2014). We now demonstrate...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Haldipur, Parthiv, Dang, Derek, Aldinger, Kimberly A, Janson, Olivia K, Guimiot, Fabien, Adle-Biasette, Homa, Dobyns, William B, Siebert, Joseph R, Russo, Rosa, Millen, Kathleen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Developmental Biology and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271606/
https://ncbi.nlm.nih.gov/pubmed/28092268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20898
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