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Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells

AIMS: Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile...

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發表在:PLoS One
Main Authors: Cataldo, Luis Rodrigo, Mizgier, María L., Bravo Sagua, Roberto, Jaña, Fabián, Cárdenas, César, Llanos, Paola, Busso, Dolores, Olmos, Pablo, Galgani, José E., Santos, José L., Cortés, Víctor A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271329/
https://ncbi.nlm.nih.gov/pubmed/28129327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170213
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