Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells

AIMS: Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Cataldo, Luis Rodrigo, Mizgier, María L., Bravo Sagua, Roberto, Jaña, Fabián, Cárdenas, César, Llanos, Paola, Busso, Dolores, Olmos, Pablo, Galgani, José E., Santos, José L., Cortés, Víctor A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271329/
https://ncbi.nlm.nih.gov/pubmed/28129327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170213
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