Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells

AIMS: Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile...

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Veröffentlicht in:PLoS One
Hauptverfasser: Cataldo, Luis Rodrigo, Mizgier, María L., Bravo Sagua, Roberto, Jaña, Fabián, Cárdenas, César, Llanos, Paola, Busso, Dolores, Olmos, Pablo, Galgani, José E., Santos, José L., Cortés, Víctor A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271329/
https://ncbi.nlm.nih.gov/pubmed/28129327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170213
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