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Distinct signaling programs control human hematopoietic stem cell survival and proliferation

Several growth factors (GFs) that together promote quiescent human hematopoietic stem cell (HSC) expansion ex vivo have been identified; however, the molecular mechanisms by which these GFs regulate the survival, proliferation. and differentiation of human HSCs remain poorly understood. We now descr...

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Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Knapp, David J. H. F., Hammond, Colin A., Aghaeepour, Nima, Miller, Paul H., Pellacani, Davide, Beer, Philip A., Sachs, Karen, Qiao, Wenlian, Wang, WeiJia, Humphries, R. Keith, Sauvageau, Guy, Zandstra, Peter W., Bendall, Sean C., Nolan, Garry P., Hansen, Carl, Eaves, Connie J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271174/
https://ncbi.nlm.nih.gov/pubmed/27827829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-740654
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