Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging

Centenarians not only enjoy an extraordinary aging, but also show a compression of morbidity. Using functional transcriptomic analysis of peripheral blood mononuclear cells (PMBC) we identified 1721 mRNAs differentially expressed by centenarians when compared with septuagenarians and young people. S...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging (Albany NY)
Päätekijät: Borras, Consuelo, M. Abdelaziz, Kheira, Gambini, Juan, Serna, Eva, Inglés, Marta, de la Fuente, Monica, Garcia, Idoia, Matheu, Ander, Sanchís, Paula, Belenguer, Angel, Errigo, Alessandra, Avellana, Juan- Antonio, Barettino, Ana, Lloret-Fernández, Carla, Flames, Nuria, Pes, Gianni, Rodriguez-Mañas, Leocadio, Viña, Jose
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270663/
https://ncbi.nlm.nih.gov/pubmed/27794564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101078
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia