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Centenarians, but not octogenarians, up-regulate the expression of microRNAs
Centenarians exhibit extreme longevity and a remarkable compression of morbidity. They have a unique capacity to maintain homeostatic mechanisms. Since small non-coding RNAs (including microRNAs) are implicated in the regulation of gene expression, we hypothesised that longevity of centenarians may...
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Hauptverfasser: | , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Nature Publishing Group
2012
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518811/ https://ncbi.nlm.nih.gov/pubmed/23233880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00961 |
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