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Convergent Mechanistic Features between the Structurally Diverse N- and O-Methyltransferases: Glycine N-Methyltransferase and Catechol O-Methyltransferase

[Image: see text] Although an enormous and still growing number of biologically diverse methyltransferases have been reported and identified, a comprehensive understanding of the enzymatic methyl transfer mechanism is still lacking. Glycine N-methyltransferase (GNMT), a member of the family that act...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Zhang, Jianyu, Klinman, Judith P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2016
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270642/
https://ncbi.nlm.nih.gov/pubmed/27355841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03462
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