Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity

Despite the wealth of knowledge of transcription factors involved in lens development, little information exists about the role of DNA methylation in this process. Here, we investigated the role of DNA methylation in lens development and fiber cell differentiation using mice conditionally lacking ma...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Hoang, Thanh V., Horowitz, Evan R., Chaffee, Blake R., Qi, Peipei, Flake, Rachel E., Bruney, Devin G., Rasor, Blake J., Rosalez, Savana E., Wagner, Brad D., Robinson, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270636/
https://ncbi.nlm.nih.gov/pubmed/27824296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1253651
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