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The green tea polyphenol EGCG alleviates maternal diabetes–induced neural tube defects by inhibiting DNA hypermethylation

BACKGROUND: Maternal diabetes increases the risk of neural tube defects in offspring. Our previous study demonstrated that the green tea polyphenol, Epigallocatechin gallate, inhibits high glucose-induced neural tube defects in cultured embryos. However, the therapeutic effect of Epigallocatechin ga...

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Publicat a:Am J Obstet Gynecol
Autors principals: Zhong, Jianxiang, Xu, Cheng, Albert Reece, E., Yang, Peixin
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270539/
https://ncbi.nlm.nih.gov/pubmed/26979632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2016.03.009
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