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Using the minimum description length principle to reduce the rate of false positives of best-fit algorithms

The inference of gene regulatory networks is a core problem in systems biology. Many inference algorithms have been proposed and all suffer from false positives. In this paper, we use the minimum description length (MDL) principle to reduce the rate of false positives for best-fit algorithms. The pe...

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Détails bibliographiques
Publié dans:EURASIP J Bioinform Syst Biol
Auteurs principaux: Fang, Jie, Ouyang, Hongjia, Shen, Liangzhong, Dougherty, Edward R, Liu, Wenbin
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270450/
https://ncbi.nlm.nih.gov/pubmed/28194163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13637-014-0013-2
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