Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway

Hyperglycemia-induced reactive oxygen species (ROS) generation contributes to development of diabetic cardiomyopathy (DCM). This study was designed to determine the effect of an antioxidant butin (BUT) on ischemia/reperfusion-induced myocardial injury in diabetic mice. Myocardial ischemia/reperfusio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Duan, Jialin, Guan, Yue, Mu, Fei, Guo, Chao, Zhang, Enhu, Yin, Ying, Wei, Guo, Zhu, Yanrong, Cui, Jia, Cao, Jinyi, Weng, Yan, Wang, Yanhua, Xi, Miaomiao, Wen, Aidong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269748/
https://ncbi.nlm.nih.gov/pubmed/28128361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41491
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