Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage IL-1β Production

OBJECTIVE: The calcium composition of atherosclerotic plaque is thought to be associated with increased risk for cardiovascular events, but whether plaque calcium itself is predictive of worsening clinical outcomes remains highly controversial. Inflammation is likely a key mediator of vascular calci...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Ceneri, Nicolle, Zhao, Lina, Young, Bryan D., Healy, Abigail, Coskun, Suleyman, Vasavada, Hema, Yarovinsky, Timur O., Ike, Kenneth, Pardi, Ruggero, Qin, Lingfen, Qin, Li, Tellides, George, Hirschi, Karen, Meadows, Judith, Soufer, Robert, Chun, Hyung J., Sadeghi, Mehran M., Bender, Jeffrey R., Morrison, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269510/
https://ncbi.nlm.nih.gov/pubmed/27834690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308507
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