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Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage IL-1β Production

OBJECTIVE: The calcium composition of atherosclerotic plaque is thought to be associated with increased risk for cardiovascular events, but whether plaque calcium itself is predictive of worsening clinical outcomes remains highly controversial. Inflammation is likely a key mediator of vascular calci...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Ceneri, Nicolle, Zhao, Lina, Young, Bryan D., Healy, Abigail, Coskun, Suleyman, Vasavada, Hema, Yarovinsky, Timur O., Ike, Kenneth, Pardi, Ruggero, Qin, Lingfen, Qin, Li, Tellides, George, Hirschi, Karen, Meadows, Judith, Soufer, Robert, Chun, Hyung J., Sadeghi, Mehran M., Bender, Jeffrey R., Morrison, Alan R.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269510/
https://ncbi.nlm.nih.gov/pubmed/27834690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308507
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