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Interleukin-21 Drives Proliferation and Differentiation of Porcine Memory B Cells into Antibody Secreting Cells

Immunological prevention of infectious disease, especially viral, is based on antigen-specific long-lived memory B cells. To test for cellular proliferation and differentiation factors in swine, an outbred model for humans, CD21(+) B cells were activated in vitro with CD40L and stimulated with purpo...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Rahe, Michael C., Murtaugh, Michael P.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268775/
https://ncbi.nlm.nih.gov/pubmed/28125737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171171
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