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Interleukin-21 Drives Proliferation and Differentiation of Porcine Memory B Cells into Antibody Secreting Cells

Immunological prevention of infectious disease, especially viral, is based on antigen-specific long-lived memory B cells. To test for cellular proliferation and differentiation factors in swine, an outbred model for humans, CD21(+) B cells were activated in vitro with CD40L and stimulated with purpo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rahe, Michael C., Murtaugh, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268775/
https://ncbi.nlm.nih.gov/pubmed/28125737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171171
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