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Selective induction of gene expression and second-messenger accumulation in Dictyostelium discoideum by the partial chemotactic antagonist 8-p-chlorophenylthioadenosine 3',5'-cyclic monophosphate.

During development of the cellular slime mold Dictyostelium discoideum, cAMP induces chemotaxis and expression of different classes of genes by means of interaction with surface cAMP receptors. We describe a cAMP derivative, 8-p-chlorophenylthioadenosine 3',5'-cyclic monophosphate (8-CPT-cAMP), whic...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Peters, D J, Bominaar, A A, Snaar-Jagalska, B E, Brandt, R, Van Haastert, P J, Ceccarelli, A, Williams, J G, Schaap, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11607223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.9219
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