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Selective induction of gene expression and second-messenger accumulation in Dictyostelium discoideum by the partial chemotactic antagonist 8-p-chlorophenylthioadenosine 3',5'-cyclic monophosphate.

During development of the cellular slime mold Dictyostelium discoideum, cAMP induces chemotaxis and expression of different classes of genes by means of interaction with surface cAMP receptors. We describe a cAMP derivative, 8-p-chlorophenylthioadenosine 3',5'-cyclic monophosphate (8-CPT-cAMP), whic...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Peters, D J, Bominaar, A A, Snaar-Jagalska, B E, Brandt, R, Van Haastert, P J, Ceccarelli, A, Williams, J G, Schaap, P
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1991
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11607223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.9219
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