Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2

Mutations of hepatocyte growth factor activator inhibitor (HAI)-2 in humans cause sodium loss in the gastrointestinal (GI) tract in patients with syndromic congenital sodium diarrhea (SCSD). Aberrant regulation of HAI-2 target protease(s) was proposed as the cause of the disease. Here functional lin...

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Publicado no:PLoS One
Main Authors: Shiao, Frank, Liu, Li-Ching O., Huang, Nanxi, Lai, Ying-Jung J., Barndt, Robert J., Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D., Lin, Chen-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268426/
https://ncbi.nlm.nih.gov/pubmed/28125689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170944
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