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Crumbs2 Promotes Cell Ingression During the Epithelial-to-Mesenchymal Transition at Gastrulation
During gastrulation of the mouse embryo, individual cells ingress in an apparently stochastic pattern during the epithelial-to-mesenchymal transition (EMT). Here we define a critical role of the apical protein Crumbs2 (CRB2) in the gastrulation EMT. Static and live imaging show that ingressing cells...
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| Udgivet i: | Nat Cell Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5268168/ https://ncbi.nlm.nih.gov/pubmed/27870829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3442 |
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