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Crumbs2 Promotes Cell Ingression During the Epithelial-to-Mesenchymal Transition at Gastrulation

During gastrulation of the mouse embryo, individual cells ingress in an apparently stochastic pattern during the epithelial-to-mesenchymal transition (EMT). Here we define a critical role of the apical protein Crumbs2 (CRB2) in the gastrulation EMT. Static and live imaging show that ingressing cells...

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書誌詳細
出版年:Nat Cell Biol
主要な著者: Ramkumar, Nitya, Omelchenko, Tatiana, Silva-Gagliardi, Nancy F., McGlade, C. Jane, Wijnholds, Jan, Anderson, Kathryn V.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268168/
https://ncbi.nlm.nih.gov/pubmed/27870829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3442
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