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Acquired uniparental disomy of chromosome 9p in hematological malignancies

Acquired uniparental disomy (aUPD) is a common and recurrent molecular event in human cancers, which leads to homozygosity for tumor suppressor genes as well as oncogenes, while retaining diploid chromosomal complement. Due to the lack of copy number change, aUPD is undetectable by comparative genom...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Wang, Linghua, Wheeler, David A., Prchal, Josef T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268131/
https://ncbi.nlm.nih.gov/pubmed/26646991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.11.005
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