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Bidirectional control of generalized epilepsy networks via rapid real-time switching of firing mode

Thalamic relay neurons have well-characterized dual firing modes: bursting and tonic spiking. Studies in brain slices have led to a model in which rhythmic synchronized spiking (phasic firing) in a population of relay neurons leads to hyper-synchronous oscillatory cortico-thalamo-cortical rhythms th...

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Bibliographische Detailangaben
Veröffentlicht in:Neuron
Hauptverfasser: Sorokin, Jordan M., Davidson, Thomas J., Frechette, Eric, Abramian, Armen M., Deisseroth, Karl, Huguenard, John R., Paz, Jeanne T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268077/
https://ncbi.nlm.nih.gov/pubmed/27989462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.11.026
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