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Closed-loop optogenetic control of thalamus as a new tool to interrupt seizures after cortical injury

Cerebrocortical injuries, such as stroke, are a major source of disability. Maladaptive consequences can result from post-injury local reorganization of cortical circuits. For example, epilepsy is a common sequela of cortical stroke, yet mechanisms responsible for seizures following cortical injurie...

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Bibliographic Details
Main Authors: Paz, Jeanne T., Davidson, Thomas J., Frechette, Eric S., Delord, Bruno, Parada, Isabel, Peng, Kathy, Deisseroth, Karl, Huguenard, John R.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700812/
https://ncbi.nlm.nih.gov/pubmed/23143518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3269
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