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Performance of toxicity probability interval based designs in contrast to the continual reassessment method

Toxicity probability interval designs have received increasing attention as a dose-finding method in recent years. In this study, we compared the two-stage, likelihood-based continual reassessment method (CRM), modified toxicity probability interval (mTPI), and the Bayesian optimal interval design (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stat Med
Hauptverfasser: Horton, Bethany Jablonski, Wages, Nolan A., Conaway, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267938/
https://ncbi.nlm.nih.gov/pubmed/27435150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7043
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