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G Protein–Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands
The ability of chemically distinct ligands to produce different effects on the same G protein–coupled receptor (GPCR) has interesting therapeutic implications, but, if excessively propagated downstream, would introduce biologic noise compromising cognate ligand detection. We asked whether cells have...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5267521/ https://ncbi.nlm.nih.gov/pubmed/27879340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106369 |
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