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HTP Nutraceutical Screening for Histone Deacetylase Inhibitors and Effects of HDACis on Tumor-suppressing miRNAs by Trichostatin A and Grapeseed (Vitis vinifera) in HeLa cells

Background/Aim: Aggressive tumor malignancies are a consequence of delayed diagnosis, epigenetic/phenotype changes and chemo-radiation resistance. Histone deacetylases (HDACs) are a major epigenetic regulator of transcriptional repression, which are highly overexpressed in advanced malignancy. While...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Genomics Proteomics
Prif Awduron: MAZZIO, ELIZABETH A., SOLIMAN, KARAM F.A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Institute of Anticancer Research 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267498/
https://ncbi.nlm.nih.gov/pubmed/28031235
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