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Insights into genome architecture deduced from the properties of short Lac repressor-mediated DNA loops

Genomic DNA is vastly longer than the space allotted to it in a cell. The molecule must fold with a level of organization that satisfies the imposed spatial constraints as well as allow for the processing of genetic information. Key players in this organization include the negative supercoiling of D...

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Detalles Bibliográficos
Publicado en:Biophys Rev
Main Authors: Perez, Pamela J., Olson, Wilma K.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267335/
https://ncbi.nlm.nih.gov/pubmed/28133491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-016-0209-7
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