Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations

Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to inflammation, brain damage and neurocognitive impairment. Paired blood and cerebrospinal fluid (CSF) were collected from 16 HIV-infected indivi...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Oliveira, Michelli F., Chaillon, Antoine, Nakazawa, Masato, Vargas, Milenka, Letendre, Scott L., Strain, Matthew C., Ellis, Ronald J., Morris, Sheldon, Little, Susan J., Smith, Davey M., Gianella, Sara
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266327/
https://ncbi.nlm.nih.gov/pubmed/28046096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006112
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