Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations

Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to inflammation, brain damage and neurocognitive impairment. Paired blood and cerebrospinal fluid (CSF) were collected from 16 HIV-infected indivi...

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Publicat a:PLoS Pathog
Autors principals: Oliveira, Michelli F., Chaillon, Antoine, Nakazawa, Masato, Vargas, Milenka, Letendre, Scott L., Strain, Matthew C., Ellis, Ronald J., Morris, Sheldon, Little, Susan J., Smith, Davey M., Gianella, Sara
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266327/
https://ncbi.nlm.nih.gov/pubmed/28046096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006112
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