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Bleomycin-resistance gene derived from the transposon Tn5 confers selective advantage to Escherichia coli K-12.

The plasmid pRAB2 contains a silent operon derived from the transposon Tn5 and carrying the gene neo for neomycin-kanamycin resistance and a truncated ble gene (ble333) for bleomycin resistance. Spontaneous mutants that express the two resistances provide Escherichia coli cells an improved fitness d...

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Autores principales: Blot, M, Meyer, J, Arber, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC52662/
https://ncbi.nlm.nih.gov/pubmed/1717996
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