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Bleomycin increases amikacin and streptomycin resistance in Escherichia coli harboring transposon Tn5.

The antitumor antibiotic bleomycin acts as a transcriptional inducer of the neo-ble-str operon of the transposon Tn5, increasing the resistance level to streptomycin and amikacin in Tn5-containing Escherichia coli. The mechanism may involve a recA-independent induction mediated by DNA damage.

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Bibliografske podrobnosti
Main Authors: Blazquez, J, Martinez, J L, Baquero, F
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC188104/
https://ncbi.nlm.nih.gov/pubmed/7694544
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