Bleomycin increases amikacin and streptomycin resistance in Escherichia coli harboring transposon Tn5.
The antitumor antibiotic bleomycin acts as a transcriptional inducer of the neo-ble-str operon of the transposon Tn5, increasing the resistance level to streptomycin and amikacin in Tn5-containing Escherichia coli. The mechanism may involve a recA-independent induction mediated by DNA damage. IMAGES...
Uloženo v:
| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7694544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.1982 |
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