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The Relaxation Properties of Myofibrils Are Compromised by Amino Acids that Stabilize α-Tropomyosin

We investigated the functional impact of α-tropomyosin (Tm) substituted with one (D137L) or two (D137L/G126R) stabilizing amino acid substitutions on the mechanical behavior of rabbit psoas skeletal myofibrils by replacing endogenous Tm and troponin (Tn) with recombinant Tm mutants and purified skel...

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Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Scellini, Beatrice, Piroddi, Nicoletta, Matyushenko, Alexander M., Levitsky, Dmitrii I., Poggesi, Corrado, Lehrer, Sherwin S., Tesi, Chiara
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2017
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266141/
https://ncbi.nlm.nih.gov/pubmed/28122223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.013
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