Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness. Fenofibrate treatment in type 2 diabetes patients reduces progression of diabetic retinopathy independent of its peroxisome proliferator-activated r...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Gong, Yan, Shao, Zhuo, Fu, Zhongjie, Edin, Matthew L., Sun, Ye, Liegl, Raffael G., Wang, Zhongxiao, Liu, Chi-Hsiu, Burnim, Samuel B., Meng, Steven S., Lih, Fred B., SanGiovanni, John Paul, Zeldin, Darryl C., Hellström, Ann, Smith, Lois E.H.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264653/
https://ncbi.nlm.nih.gov/pubmed/27720395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.09.025
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