Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody()

The Staphylococcus aureus fibrinogen binding MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules), ClfA (clumping factor A) is an important virulence factor in staphylococcal infections and a component of several vaccines currently under clinical evaluation. The mouse monoclo...

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Publicado en:EBioMedicine
Autores principales: Ganesh, Vannakambadi K., Liang, Xiaowen, Geoghegan, Joan A., Cohen, Ana Luisa V., Venugopalan, Nagarajan, Foster, Timothy J, Hook, Magnus
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264652/
https://ncbi.nlm.nih.gov/pubmed/27789272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.09.027
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