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Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody()

The Staphylococcus aureus fibrinogen binding MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules), ClfA (clumping factor A) is an important virulence factor in staphylococcal infections and a component of several vaccines currently under clinical evaluation. The mouse monoclo...

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Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Ganesh, Vannakambadi K., Liang, Xiaowen, Geoghegan, Joan A., Cohen, Ana Luisa V., Venugopalan, Nagarajan, Foster, Timothy J, Hook, Magnus
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264652/
https://ncbi.nlm.nih.gov/pubmed/27789272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.09.027
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