Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody()

The Staphylococcus aureus fibrinogen binding MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules), ClfA (clumping factor A) is an important virulence factor in staphylococcal infections and a component of several vaccines currently under clinical evaluation. The mouse monoclo...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ganesh, Vannakambadi K., Liang, Xiaowen, Geoghegan, Joan A., Cohen, Ana Luisa V., Venugopalan, Nagarajan, Foster, Timothy J, Hook, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264652/
https://ncbi.nlm.nih.gov/pubmed/27789272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.09.027
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